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Andreas Höglund Selected Research

dCTP pyrophosphatase

1/2017Piperazin-1-ylpyridazine Derivatives Are a Novel Class of Human dCTP Pyrophosphatase 1 Inhibitors.
1/2017Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.
2/2016Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1.

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Andreas Höglund Research Topics

Disease

9Neoplasms (Cancer)
11/2021 - 04/2009
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2021 - 08/2014
2Hematologic Neoplasms (Hematological Malignancy)
11/2021 - 02/2017
2Lymphoma (Lymphomas)
10/2011 - 04/2009
1Cockayne Syndrome (Syndrome, Cockayne)
10/2018
1Leukemia
02/2016
1Carcinoma (Carcinomatosis)
02/2016
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2011
1Disease Progression
10/2011
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
04/2009
1Burkitt Lymphoma (Burkitt's Lymphoma)
04/2009
1Aneuploidy (Aneuploid)
04/2009
1Necrosis
01/2009

Drug/Important Bio-Agent (IBA)

3NucleotidesIBA
11/2021 - 01/2017
3DNA (Deoxyribonucleic Acid)IBA
11/2021 - 04/2009
3Proteins (Proteins, Gene)FDA Link
10/2018 - 04/2009
3dCTP pyrophosphataseIBA
01/2017 - 02/2016
2Reactive Oxygen Species (Oxygen Radicals)IBA
11/2021 - 04/2014
2EnzymesIBA
10/2017 - 01/2017
2DecitabineFDA Link
08/2014 - 04/2009
2Pharmaceutical PreparationsIBA
11/2011 - 04/2009
1karonudibIBA
11/2021
1IgA receptor (protein B)IBA
10/2018
1A-Form DNA (A-DNA)IBA
10/2018
1AntioxidantsIBA
10/2017
1DeoxycytidineIBA
02/2017
1Cytarabine (Cytosar-U)FDA LinkGeneric
02/2017
1Cytostatic AgentsIBA
02/2017
1NucleosidesIBA
01/2017
1CytidineIBA
02/2016
1Checkpoint Kinase 1IBA
11/2011
13- (carbamoylamino)- 5- (3- fluorophenyl)- N- (3- piperidyl)thiophene- 2- carboxamideIBA
10/2011
1Transcription Factors (Transcription Factor)IBA
10/2011
1CaspasesIBA
04/2009
1MethyltransferasesIBA
04/2009
1Messenger RNA (mRNA)IBA
01/2009

Therapy/Procedure

1Therapeutics
02/2017